B4gat1 (beta-1,4-glucuronyltransferase 1)

基因基本信息

B4gat1 基因表型（MGI）

Mice homozygous for a null allele display altered lymphocyte rolling and abnormal lymph node B and T cell numbers. Homozygotes for a different null allele are embryonic lethal and show small embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, and failure to gastrulate. Homozygotes for a hypomorphic allele show mild muscular dystrophy, abnormal axon guidance and fasciculation, and abnormal dorsal funiculus.

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