Pcca (propionyl-Coenzyme A carboxylase, alpha polypeptide)

基因基本信息

Pcca 基因表型（MGI）

Homozygous null mice die 24-36 hours after birth due to accelerated ketoacidosis. Death is preceded by reduced milk intake, poor movement, dehydration, accumulation of propionyl-CoA, ketonuria, increased fat deposition and glycogen consumption in liver, and enlarged kidney collecting ducts.

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