Adam2 (a disintegrin and metallopeptidase domain 2)

基因基本信息

Adam2 基因表型（MGI）

Mice homozygous for targeted mutations that inactivate the gene are viable, females are fertile, but males have severely reduced fertility. Mutant male sperm are defective in sperm-egg membrane adhesion, sperm-egg fusion, migration from the uterus to theoviduct, and binding to the egg zona pellucida.

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