Alox12b (arachidonate 12-lipoxygenase, 12R type)

基因基本信息

Alox12b 基因表型（MGI）

Neonatal homozygous mutant mice exhibit reddened skin that quickly dehydrates and appears scaly. The epidermis is hyperkeratotic, and its permeability barrier function is compromised. Homozygotes die within 24 hours of birth.

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