Bdnf (brain derived neurotrophic factor)

基因基本信息

Bdnf 基因表型（MGI）

Homozygotes for targeted null alleles exhibit sensory neuron losses affecting coordination, balance, hearing, taste, and breathing, cerebellar abnormalities, increased sympathetic neuron number, and postnatal lethality. Carriers show mild defects. Heterozygosity for a mutation that reduces levels of the mature form of the encoded peptide leads to depressive-like behavior.

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