Cask 基因位于小鼠第 X 号染色体(X A1.1|X 8.43 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。
| 基因符号 | Cask |
|---|---|
| 英文全称 | calcium/calmodulin dependent serine protein kinase |
| 别名 | DXPri1 | DXRib1 | LIN-2 | Pals3 | mLin-2 |
| 染色体 | X |
| 染色体定位 | X A1.1|X 8.43 cM |
| 基因类型 | protein-coding |
| MGI 编号 | MGI:1309489 |
Mutation of this gene results in cleft palate and perinatal lethality in hemizygous males and death within 2 weeks in females on a C57BL/6J background. Some female animals on a CD1 background survive to adulthood exhibiting patchy fur, wrinkled skin, a kinked tail and spine, and give birth to small and infrequent litters. Male and female animals on all genetic backgrounds exhibit reduced head size, shortened jaw, and a pointed snout.
鼠来宝提供 Cask 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。
查看 Cask 在线模型 了解鼠来宝服务