Runx1t1 (RUNX1 translocation partner 1)

基因基本信息

Runx1t1 基因表型（MGI）

Homozygous disruption of this gene results in increased perinatal lethality and surviving animals show severe growth retardation. The midgut is absent in 25% of mutant animals which could explain increased perinatal mortality. Surviving animals display thinned intestinal walls and dilated lumens. Heterozygosity for the p.Y534H allele suppresses tumor development in a MYCN-driven neuroblastoma mouse model on a 129X1/SvJ background.

获取 Runx1t1 基因编辑小鼠

鼠来宝提供 Runx1t1 相关基因敲除、条件敲除、人源化、点突变小鼠定制，以及配套动物实验、代养净化、检测研发服务。双繁育基地（鄂州葛店·广东佛山），标准化笼位 10 万+。