Cpe (carboxypeptidase E)

基因基本信息

Cpe 基因表型（MGI）

Mice homozygous for a spontaneous or a targeted null mutation display progressive obesity, abnormal blood glucose and lipid regulation, and have reduced fertility. Aberrant prohormone processing and secretion appears to be the cause of these phenotypes. Homozygous KO or homozygosity for an enzymatically inactive mutant leads to depressive-like behavior, in addition to obesity, blood glucose dis-regulation and infertility. KO also leads to hippocampal neurodegeneration after stress and impaired spatial learning and memory.

获取 Cpe 基因编辑小鼠

鼠来宝提供 Cpe 相关基因敲除、条件敲除、人源化、点突变小鼠定制，以及配套动物实验、代养净化、检测研发服务。双繁育基地（鄂州葛店·广东佛山），标准化笼位 10 万+。