Foxa3 基因位于小鼠第 7 号染色体(7 A3|7 9.46 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。
| 基因符号 | Foxa3 |
|---|---|
| 英文全称 | forkhead box A3 |
| 别名 | Hnf-3g | Hnf3g | Tcf-3g | Tcf3g |
| 染色体 | 7 |
| 染色体定位 | 7 A3|7 9.46 cM |
| 基因类型 | protein-coding |
| MGI 编号 | MGI:1347477 |
Homozygotes for a targeted null mutation exhibit reduced expression of several liver-specific and liver-enriched genes. Homozygous mice exhibit abnormal glucose homeostasis and reduced male fertility with abnormal spermatogeneis. Mice remodel their fat tissues on high fat diets, store less fat, and burn more energy as they age. Mutant mice live significantly longer than controls.
鼠来宝提供 Foxa3 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。
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