Kif5a (kinesin family member 5A)

基因基本信息

Kif5a 基因表型（MGI）

Homozygous inactivation of this gene causes complete neonatal lethality. Homozygotes delivered by caesarian section are alive at E18.5 but usually die within minutes after birth, exhibiting an abnormal breathing pattern, atelectasis, cyanosis, and abnormal motor neuron morphology in the spinal cord. Mice carrying a splice donor site mutation in the penultimate intron show delayed and incomplete sciatic nerve crush injury recovery.

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