Lgals3 (lectin, galactose binding, soluble 3)

基因基本信息

Lgals3 基因表型（MGI）

Homozygotes for a null allele show susceptibility to S. pneumoniae infection, resistance to renal fibrosis, defects in chondrocyte differentiation, and impaired macrophage activation. Homozygotes for another null allele show altered peritoneal inflammation, and susceptibility to T. gondii infection. Homozygosity for a glycan-binding deficient mutation leads to increased vertebral bone density in aged female mice.

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