Maz 基因位于小鼠第 7 号染色体(7 F3|7 69.28 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。
| 基因符号 | Maz |
|---|---|
| 英文全称 | MYC-associated zinc finger protein (purine-binding transcription factor) |
| 别名 | MAZI | PUR1 | Pur-1 | SAF-1 | SAF-2 |
| 染色体 | 7 |
| 染色体定位 | 7 F3|7 69.28 cM |
| 基因类型 | protein-coding |
| MGI 编号 | MGI:1338823 |
Mice homozygous for a knock-out allele exhibit fetal and postnatal lethality, kidney agenesis, and abnormal atrial size and male infertility in rare surviving mice. Mice heterozygous for the same allele exhibit fetal lethality and abnormal bladder function and architecture. Adult mice heterozygous for a different knock-out allele show decreased cingulate cortex size in both sexes, and male-specific neuroanatomical phenotypes including small lateral ventricles, decreased corpus callosum, internal capsule and habenula size, and increased secondary somatosensory cortex size.
鼠来宝提供 Maz 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。
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