Pak1 (p21 (RAC1) activated kinase 1)

基因基本信息

Pak1 基因表型（MGI）

Mice homozygous for a knock-out allele display defects in allergen-induced mast cell migration and degranulation. Mice homozygous for a different knock-out allele exhibit reduced long term potentiation. A C>T mutation at position 6 in the 3' UTR affects the use of the proximal poly(A) signal and reduces susceptibility to developing papillomas.

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