Pten (phosphatase and tensin homolog)

基因基本信息

Pten 基因表型（MGI）

Homozygous null mutants die by E9.5 with abnormally patterned enlarged brains and defective placentas. Heterozygotes develop a range of neoplasms. Conditional mutants demonstrate effects on basic processes of proliferation, differentiation and apoptosis. KO of the alpha isoform affects mitophagy and causes olfactory, spatial learning and contextual fear memory deficits and increases susceptibility to induced cardiac injury.

获取 Pten 基因编辑小鼠

鼠来宝提供 Pten 相关基因敲除、条件敲除、人源化、点突变小鼠定制，以及配套动物实验、代养净化、检测研发服务。双繁育基地（鄂州葛店·广东佛山），标准化笼位 10 万+。