Casc3 (exon junction complex subunit)

基因基本信息

Casc3 基因表型（MGI）

Homozygous null mice show decreased embryo size and embryonic lethality. Homozygotes for one knock-out allele exhibit absent primitive node and head folds, and failure to gastrulate. Homozygotes for a hypomorphic allele show delayed fetal growth and limb development and complete lethality during fetal growth through weaning.

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