Ranbp2 (RAN binding protein 2)

基因基本信息

Ranbp2 基因表型（MGI）

Mice homozygous for a knock-out allele show abnormal morula morphology and complete embryonic lethality before implantation, with failure of blastocyst formation in in-vitro outgrowth assays. Mice homozygous for a gene trap allele are embryonic lethal, while heterozygotes display reduced ATP levels in the CNS, decreased glucose clearance, decreased susceptibility to diet-induced obesity, and reduced scotopic responses on some backgrounds .

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