Sh2b1 (SH2B adaptor protein 1)

基因基本信息

Sh2b1 基因表型（MGI）

Homozygous null mice are infertile. Female mice have small, anovulatory ovaries with reduced numbers of follicles and male mice exhibit small testes and sperm deficits. Mice homozygous for a floxed allele activated in the pancreas exhibit impaired glucose homeostasis when fed a high fat diet.

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