Smarcb1 (SWI/SNF related BAF chromatin remodeling complex subunit B1)

基因基本信息

Smarcb1 基因表型（MGI）

Homozygous inactivation of this gene leads to peri-implantation lethality, likely due to an inability of the blastocysts to hatch and implant in the uterus. A subset of heterozygous null mice develop a variety of tumors in the soft tissues of the head and neck. Homozygosity for a C-terminus extending mutation affects brain development, often leading to hydrocephalus, and leads to slow weight gain.

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