Trim28 (tripartite motif-containing 28)

基因基本信息

Trim28 基因表型（MGI）

Homozygotes for a targeted disruption of this gene develop normally until the blastocyst stage and undergo uterine implantation, but become arrested at the early egg-cylinder stage, fail to gastrulate, and are completely resorbed by E8.5. Conditional homozygous KO in ovaries leads to masculinization of follicles.

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