Ube2i (ubiquitin-conjugating enzyme E2I)

基因基本信息

Ube2i 基因表型（MGI）

Embryos homozygous for a targeted null mutation die prior to E7.5. In culture, mutant blastocysts are viable up to 2 days but show subsequent apoptosis of the inner cell mass. Mutant cells exhibit major chromosome condensation and segregation defects as well as gross defects in nuclear organization.

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