Yap1 (yes-associated protein 1)

基因基本信息

Yap1 基因表型（MGI）

Embryos homozygous for a null mutation of this gene die between embryonic days E9.5 and E10.5 due to yolk sac avasculogenesis and failure of attachment between the allantois and the chorion. Heterozygous mice are viable, and fertile but exhibit age-dependent cone photoreceptor degeneration and retinal abnormalities. An inducible acetylation-blocking allele leads to improved post-injury cardiac regeneration.

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