Gpbar1 (G protein-coupled bile acid receptor 1)

基因基本信息

Gpbar1 基因表型（MGI）

Mutations in this gene result in abnormal cholesterol, bile, and insulin homeostasis. Mice homozygous for a conditional allele activated in adipose tissue are resistant to the improvements in adipose tissue thermogenesis that occur in the diet-induced obesity model of intestine-specific Hif1a knockout.

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