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Zic2 (zinc finger protein of the cerebellum 2)

Zic2 基因位于小鼠第 14 号染色体(14 E5|14 65.97 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。

基因基本信息

基因符号Zic2
英文全称zinc finger protein of the cerebellum 2
别名HPE5 | Ku
染色体14
染色体定位14 E5|14 65.97 cM
基因类型protein-coding
MGI 编号MGI:106679

Zic2 基因表型(MGI)

Defects in neurulation and forebrain development have been identified in both targeted and ENU induced homozygous mutants. Death occurs perinatally in the targeted mouse and during midgestation in the ENU mouse. Mice homozygous for a knock-down allele exhibit cognitive and social behavior defects. A critical mutation in the last zinc finger domain results in multiple isomerism-related and other malformations in the embryonic brain, eyes, heart, lungs, cardiopulmonary vasculature, and digestive organs.

获取 Zic2 基因编辑小鼠

鼠来宝提供 Zic2 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。

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