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Shroom3 (shroom family member 3)

Shroom3 基因位于小鼠第 5 号染色体(5 E2|5 47.29 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。

基因基本信息

基因符号Shroom3
英文全称shroom family member 3
别名D5Ertd287e | Shrm | Shrm3
染色体5
染色体定位5 E2|5 47.29 cM
基因类型protein-coding
MGI 编号MGI:1351655

Shroom3 基因表型(MGI)

Homozygous mutation of this locus results in failed neural tube closure leading to exencephaly, acrania, facial clefting, and spina bifida. Homozygotes develop to term but die either at birth or shortly thereafter. Homozygotes for a gene trapped allele display congenital cardiac defects, as well as disrupted cardiomyocyte polarity, organization, proliferation and maturity.

获取 Shroom3 基因编辑小鼠

鼠来宝提供 Shroom3 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。

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