Taok2 基因位于小鼠第 7 号染色体(7 F3|7 69.25 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。
| 基因符号 | Taok2 |
|---|---|
| 英文全称 | TAO kinase 2 |
| 别名 | 1110033K02Rik | B230344N16 | MAP3K17 | PSK | PSK1 | TAO1 | TAO2 | mKIAA0881 |
| 染色体 | 7 |
| 染色体定位 | 7 F3|7 69.25 cM |
| 基因类型 | protein-coding |
| MGI 编号 | MGI:1915919 |
Mice homozygous for a transgenic gene disruption exhibit decreased body size. Mice homozygous for a knock-out allele exhibit resistance to the ataxic effect of alcohol, reduced blood ethanol content, increased alcohol consumption, impaired CPP for alcohol, and impaired habituation in an open field. Adult mice heterozygous for a different knock-out allele show male-specific brain neuroanatomical phenotypes including increased total brain area, increased cingulate cortex and corpus callosum size, decreased area of the anterior commissure and dorsal hippocampal commissure, and reduced height of the primary motor cortex.
鼠来宝提供 Taok2 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。
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