Kcnd3 (potassium voltage-gated channel, Shal-related family, member 3)

基因基本信息

Kcnd3 基因表型（MGI）

Mice homozygous for a reporter (null) allele are viable and fertile and exhibit normal cardiac morphology and function, and display no ataxia phenotype. Homo- or heterozygosity for the dominant negative p.F227del mutation causes degeneration of several cellular compartments and trafficking defects, which affects neural electrophysiology and leads to motor coordination and balance deficits.

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鼠来宝提供 Kcnd3 相关基因敲除、条件敲除、人源化、点突变小鼠定制，以及配套动物实验、代养净化、检测研发服务。双繁育基地（鄂州葛店·广东佛山），标准化笼位 10 万+。