Shank3 (SH3 and multiple ankyrin repeat domains 3)

基因基本信息

Shank3 基因表型（MGI）

Mice carrying various deletions of exons encoding the ankyrin repeats (exons 4-9) exhibit a range of synaptic and autism-related impairments. Homozygotes lacking exon 9 show altered excitation/inhibition balance, increased rearing, and mildly impaired spatial memory. Knockout also affects behavior in response to physical and virtual novel objects.

获取 Shank3 基因编辑小鼠

鼠来宝提供 Shank3 相关基因敲除、条件敲除、人源化、点突变小鼠定制，以及配套动物实验、代养净化、检测研发服务。双繁育基地（鄂州葛店·广东佛山），标准化笼位 10 万+。