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Ccdc198 (coiled-coil domain containing 198)

Ccdc198 基因位于小鼠第 14 号染色体(14 C1|14 25.46 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。

基因基本信息

基因符号Ccdc198
英文全称coiled-coil domain containing 198
别名1700011H14Rik
染色体14
染色体定位14 C1|14 25.46 cM
基因类型protein-coding
MGI 编号MGI:1914332

Ccdc198 基因表型(MGI)

On the FVB/Ant background knockout mice show increased body weight, decreased locomotor activity, reduced serum ferritin levels, albuminuria, thrombocytopenia (females only), and a reduced size of kidneys, adrenal glands, interscapular brown adipose tissue and liver, which is analogous to control mice on a low iron diet. Analysis of a second knockout model on the C57BL/6NCrl background reveals significant effects in metabolic cage experiments, including differences in body weight and lean body mass, day/night activity, food intake, and energy expenditure.

获取 Ccdc198 基因编辑小鼠

鼠来宝提供 Ccdc198 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。

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