Slc39a8 (solute carrier family 39 (metal ion transporter), member 8)

基因基本信息

Slc39a8 基因表型（MGI）

Mice homozygous for a null allele die by E16.5 showing body edema, cardiac hypertrabeculation, thin compact myocardium, left ventricular noncompaction, increased cardiomyocyte proliferation, extracellular matrix accumulation, lower zinc level, and ventricular septal defects. Homozygosity for the p.A393T mutation leads to lower brain zinc levels and lower cortex dendritic spine density.

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