Tmco1 (transmembrane and coiled-coil domains 1)

基因基本信息

Tmco1 基因表型（MGI）

Homozygotes for a null allele show prenatal lethality, stunted growth, delayed osteogenesis, craniofacial anomalies, impaired coordination and spatial memory, altered Ca2+ homeostasis, and reduced survivor rate. Homozygotes for another null allele show female subfertility, impaired ovarian folliculogenesis, premature ovarian failure, and altered endoplasmic reticulum Ca2+ homeostasis in granulosa cells.

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