Appl1 (adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1)

基因基本信息

Appl1 基因表型（MGI）

Mice homozygous for a null allele exhibit decreased insulin-induced relaxation and increased insulin-induced ET-1-dependent vasoconstriction when fed a high fat diet. Homozygotes for a second null allele show increased hematocrit and T cell proliferation, and decreased fibroblast cell migration. Homozygotes for a third null allele show hyperactivity, increased body core temperature, and insulin resistance.

获取 Appl1 基因编辑小鼠

鼠来宝提供 Appl1 相关基因敲除、条件敲除、人源化、点突变小鼠定制，以及配套动物实验、代养净化、检测研发服务。双繁育基地（鄂州葛店·广东佛山），标准化笼位 10 万+。