Zmym2 (zinc finger, MYM-type 2)

基因基本信息

Zmym2 基因表型（MGI）

Homozygous inactivation of this gene results in decreased embryo size, embryonic growth retardation, and complete lethality during organogenesis. Mice homozygous for a knock-out allele exhibit embryo turning and branchial arch/pouch defects, an abnormally shaped head, heart and tail, incomplete cranial neural tube closure, abnormal yolk sac vasculature, and an expanded spongiotrophoblast layer. Mice heterozygous for a transposon induced mutation show genitourinary defects, increased anxiety and aggressive-like behaviors, and glucose metabolism disorders.

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