鼠来宝生物首页基因目录

Mvp (major vault protein)

Mvp 基因位于小鼠第 7 号染色体(7 F3|7 69.26 cM),编码 protein-coding。鼠来宝提供该基因的基因敲除小鼠、条件敲除小鼠、点突变小鼠及配套动物实验服务。

基因基本信息

基因符号Mvp
英文全称major vault protein
别名2310009M24Rik | LRP | VAULT1
染色体7
染色体定位7 F3|7 69.26 cM
基因类型protein-coding
MGI 编号MGI:1925638

Mvp 基因表型(MGI)

Mice homozygous for a knock-out allele are viable, healthy and phenotypically normal with unimpaired dendritic cell maturation and function and normal resistance to various cytostatic agents. Adult mice homozygous for a gene trapped allele show male-specific brain neuroanatomical phenotypes including decreased total brain area, small brain nuclei associated with the limbic system, reduced corpus callosum, hippocampus, thalamus and cingulate gyrus size, decreased secondary somatosensory cortex size, abnormal neuron morphology, smaller mEPSC amplitude, and decreased dendritic spine density but no major behavioral deficits

获取 Mvp 基因编辑小鼠

鼠来宝提供 Mvp 相关基因敲除、条件敲除、人源化、点突变小鼠定制,以及配套动物实验、代养净化、检测研发服务。双繁育基地(鄂州葛店·广东佛山),标准化笼位 10 万+。

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