Trem2 (triggering receptor expressed on myeloid cells 2)

基因基本信息

Trem2 基因表型（MGI）

Mice homozygous for a knock-out allele display enhanced cytokine production by macrophages in response to toll-like receptor agonists. Mice homozygous for a different knock-out allele show reduced microglial cell survival, proliferation and activation and cell cycle arrest at the G1/S checkpoint.

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